All optical interrogation of cardiac arrhythmias
By Rebecca Burton, 2021
Fellow’s Profile
Fellow’s Profile
All-optical interrogation of cardiac arrhythmias
Developing tools to understand neural-cardiac interactions and their effect on arrhythmias
2015
South East
I am a biomedical scientist with an interest in applying bioengineering methods to answer cardiac questions about causes and consequences of arrhythmias. I am based in the Department of Pharmacology, University of Oxford. In 2015 I was awarded a Churchill Fellowship in Science and Engineering which allowed me to spend time in Stony Brook University, USA.
Arrhythmias or heart rhythm problems are experienced by more than 2 million people a year in the UK alone. Certain types of arrhythmias can cause sudden cardiac death. Cardiac stimulation via sympathetic neurons can potentially trigger arrhythmias.
The research performed during my Fellowship in collaboration with colleagues in the USA and UK resulted in publication (Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics, in iScience, Volume 23, Issue 7, 24 July 2020, 101334). The highlights of the paper include: a methodology to study neuron-cardiac interactions and demonstration of optogenetic control (use of light to control neurons that have been genetically modified to express light-sensitive ion channels) of sympathetic neurons and their effects on cardiac behaviour.
By Rebecca Burton, 2021
The work of scientist Rebecca-Ann Burton (CF 2015) has been highlighted as part of the University of Oxford’s campaign 100 Women of Oxford Medical Sciences, this month. Rebecca’s Fellowship researched neural triggers of cardiac arrhythmias and she now runs her own research group.
By Rebecca Burton, 2021
Principal investigator Rebecca-Ann Burton (CF 2015) has contributed research to a report on cardiac arrhythmias which has been published in iScience. Rebecca carried out her research with a Professor of Engineering whom she met on her 2015 Fellowship during a visit to the USA.
By Rebecca Burton, 2020
All Reports are copyright © the author. The moral right of the author has been asserted. The views and opinions expressed by any Fellow are those of the Fellow and not of the Churchill Fellowship or its partners, which have no responsibility or liability for any part of them.
By Rebecca Burton, 2021
The work of scientist Rebecca-Ann Burton (CF 2015) has been highlighted as part of the University of Oxford’s campaign 100 Women of Oxford Medical Sciences, this month. Rebecca’s Fellowship researched neural triggers of cardiac arrhythmias and she now runs her own research group.
By Rebecca Burton, 2021
Principal investigator Rebecca-Ann Burton (CF 2015) has contributed research to a report on cardiac arrhythmias which has been published in iScience. Rebecca carried out her research with a Professor of Engineering whom she met on her 2015 Fellowship during a visit to the USA.
By Rebecca Burton, 2020
All Reports are copyright © the author. The moral right of the author has been asserted. The views and opinions expressed by any Fellow are those of the Fellow and not of the Churchill Fellowship or its partners, which have no responsibility or liability for any part of them.